Cancer medicines
Irinotecan
Irinotecan
A chemotherapy with an important risk of severe diarrhea.
Sources checked · Introductory guide
On this page
How it works
Inhibits topoisomerase I, disrupting DNA replication. Distinguish it from liposomal formulations.[1]
Where it is used
Used alone or with other drugs for metastatic colorectal cancer.[1]
Key safety points
Diarrhea can occur during treatment or later. Contact your team at the first episode; report fever or dehydration immediately.[2]
Questions for your care team
- What is my diarrhea action plan and when should I call?
Sources and scope
Source documents are in English.
General information based on official public sources. This is not a complete list of uses or side effects. Individual treatment decisions require your care team and current source documents. US-source uses do not establish local approval or reimbursement.