Side effects

Cytokine release syndrome

Cytokine release syndrome · CRS

An immune reaction that can occur after some immunotherapies.

Sources checked · Introductory guide

What is it?

A rapid release of cytokines from immune cells can trigger this reaction. It may be mild, but severe reactions can be life-threatening.[1]

Which symptoms should I report?

Symptoms can include fever, rapid heartbeat, low blood pressure and breathing difficulty. Contact your team immediately; severe breathing difficulty or altered consciousness needs emergency care.[1]

Questions for your care team

  • Who should I contact at night or on weekends?

Sources and scope

Source documents are in English.

  1. NCI Dictionary · Cytokine release syndrome (opens in a new tab)

General information based on official public sources. This is not a complete list of uses or side effects. Individual treatment decisions require your care team and current source documents.

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