Side effects

Hand-foot syndrome

Hand-foot syndrome

Redness and pain can affect palms and soles.

Sources checked · Introductory guide

On this page

What is it?

Some cancer medicines cause swelling, tingling and skin changes.[1]

What to track and discuss

Track effects on walking and hand use; discuss skin care.[2]

When to get help promptly

Report blisters, severe pain or difficulty walking promptly; do not change doses yourself.[2]

Questions for your care team

  • Which skin changes should prompt a call?

Sources and scope

Source documents are in English.

Entries summarize and translate linked official public sources. The source-check date records when those sources were checked; it does not indicate a clinician’s review.

  1. NCI · Hand-Foot Syndrome (opens in a new tab)
  2. MedlinePlus · Capecitabine (opens in a new tab)

General information based on official public sources. This is not a complete list of uses or side effects. Individual treatment decisions require your care team and current source documents. US-source uses do not establish local approval or reimbursement.

Related entries

Hand-foot syndrome | Cancer Encyclopedia | My Chemo Diary